贾凤菊,博士,bwin体育必赢成人护理教研室讲师。
一、研究方向
1. 老年护理研究
2. 神经退行性疾病的病因及防治对策研究
3. 慢性病管理
二、承担项目/获奖
1. 山东省自然科学基金青年项目,泛素连接酶CHIP-去泛素化酶OTUD3-铁调节蛋白IRP2调控轴在帕金森病中的作用研究,2021-01至2023-12,在研,主持。
2. 国家自然科学基金面上项目, Nesfatin-1基于脑肠轴参与帕金森病发病的机制研究, 2022-01至2025-12, 在研, 参加。
3. 国家自然科学基金面上项目, 星形胶质细胞CXCL12/CXCR7信号通路在脑缺血损伤中的作用及机制研究, 2020-01至2023-12, 在研, 参加。
4. 山东省自然科学基金重大基础研究项目,去泛素化酶OTUD3参与帕金森病黑质多巴胺能神经元死亡的分子机制研究,2019-12至2024-12,在研,参加。
5. 山东省优秀博士学位论文,2020年,唯一。
6. 山东省科技进步二等奖,2020年,第五位。
7. bwin必赢体育在线优秀博士学位论文,2019年,唯一。
8. 青岛市科技进步一等奖,2018年,第四位。
9. 山东省研究生优秀科技创新成果奖三等奖,2017年,唯一。
三、代表性论文
1. Jia F#, Li H#, Jiao Q, Li C, Fu L, Cui C, Jiang H*, Zhang L*. Deubiquitylase OTUD3 prevents Parkinson’s disease through stabilizing iron regulatory protein 2. Cell Death Dis. 2022, 13(4):418.
2. Yao Z, Fu L, Jia F, Bi M, Jiao Q, Chen X, Du X, Jiang H*. Rethinking IRPs/IRE system in neurodegenerative disorders: Looking beyond iron metabolism. Ageing Res Rev. 2022, 73: 101511.
3. 姚征洋,贾凤菊,傅琳,焦倩,陈曦,杜希恂,姜宏*。铁调节蛋白2高表达对MPP+诱导的PC12细胞损伤的影响。精准医学杂志。精准医学杂志。 2022,37(02)。
4. 王淑华,贾凤菊,焦倩,傅琳,杜希恂,陈曦,姜宏*。铁调节蛋白2高表达对PC12细胞活力及铁调节蛋白1表达水平的影响。精准医学杂志。 2022,37(01)。
5. Jia F*, Liu H, Kang S. NCOA4-Mediated Ferritinophagy: A Vicious Culprit in COVID-19 Pathogenesis? Front Mol Biosci. 2021, 8:761793.
6. Jiao L, Du X, Jia F, Zhang P, Li Y, Zhu D,Tang T, Jiao Q*, Jiang H*. Early low-dose ghrelin intervention via miniosmotic pumps could protect against the progre ssive dopaminergic neuron loss in Parkinson's disease mice, Neurobiol Aging. 2021, 101: 70-78.
7. 高艺峻,贾凤菊,焦倩,陈曦,杜希恂,姜宏*。卵巢肿瘤结构域蛋白3敲除小鼠黑质区核因子κB相关炎症因子表达的变化及其机制。精准医学杂志。2021,36(02)
8. 高子寒,杨丽*,魏晓,贾凤菊,王敏。基于Web of Sciense的延续性护理研究热点前沿可视化分析。护理学报。2021,28(04)。
9. Jia F, Song N, Wang W, Du X, Chi Y, Jiang H*. High dietary iron supplement induces the nigrostriatal dopaminergic neurons lesion in transgenic mice expressing mutant A53T human alpha-synuclein. Front Aging Neurosci. 2018, 10:97.
10. Wang W#, Song N#, Jia F, Tang T, Bao W, Zuo C, Xie J, Jiang H*. Genomic DNA levels of mutant alpha-synuclein correlate with nonmotor symptoms in an A53T Parkinson's disease mouse model. Neurochem Int. 2018, 114:71-79.6.
11. Song N#, Wang W#, Jia F, Du X, Xie A, He Q, Shen X, Zhang J, Rogers JT, Xie J, Jiang H*. Assessments of plasma ghrelin levels in the early stages of parkinson's disease. Mov Disord. 2017, 32(10):1487-1491.
12. Li Y, Jiao Q, Xu H, Du X, Shi L, Jia F, Jiang H*. Biometal dyshomeostasis and toxic metal accumulations in the development of Alzheimer's disease. Front Mol Neurosci, 2017, 10:339.
13. Jia F#, Liu Z#, Song N, Du X, Xie J, Jiang H*. The association between CYP46A1 rs4900442 polymorphism and the risk of Alzheimer's disease: A meta-analysis. Neurosci Lett. 2016, 620:83-7.
14. Jia F, Song N, Zhao C, Xie J, Jiang H*. Unexpected improvements of spatial learning and memory abilities in chronic rotenone intoxicated mice. PLoS ONE 2014, 9(3): e91641.
15. Shen X#, Jia F#, Song N, Xie J, Jiang H*. Protective effects of obestatin are mediated by proliferative rather than anti-apoptotic properties in MES23.5 dopaminergic cells. Neurosci Bull. 2014, 30(1): 118-124.
16. He Q, Song N, Jia F, Xu H, Yu X, Xie J, Jiang H*. Role of α-synuclein aggregation and the nuclear factor E2-related factor 2/heme oxygenase-1 pathway in iron-induced neurotoxicity. Int J Biochem Cell Biol. 2013, 45(6):1019-30.
四、联系方式:Email: jiafengjv@163.com